Searchable abstracts of presentations at key conferences in endocrinology

ea0007p65 | Diabetes, metabolism and cardiovascular | BES2004

Leptin increases lipid peroxidation in the mouse brain

Kutlu S , Canpolat S , Yasar A , Tuzcu M , Aydin M , Baydas G

Leptin hormone is mainly secreted from adipose tissue and has an important role in energy metabolism. There have been very few studies examining effects of leptin on oxidant stress. The aim of the present study was to investigate whether leptin affects lipid peroxidation and antioxidant status in the brain of mice. Adult male Bulb-c mice were divided into two groups. Leptin was intraperitoneally administered to the first group at a dose of 40ug/animal for 5 days. Controls rece...